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CHMP2B抗体,染色质修饰蛋白2B抗体

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0.1ml: 100ug
0.2ml: 200ug
起订: 1 支
供货总量: 100 支
发货期限: 自买家付款之日起 1 天内发货
所在地: 上海
有效期至: 长期有效
最后更新: 2017-02-06 14:22
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【CHMP2B抗体,染色质修饰蛋白2B抗体】详细说明


     上海研盟生物科技有限公司(http://www.chemdrug.com/company/)多年专业提供科研试剂(http://www.chemdrug.com/sell/21/),秉承五优政策---质量优、价格优、货期优、运输条件优、售后优。产品(http://www.chemdrug.com/invest/)质量*,规格齐全,是**重点实验室及国内各大院校长期指定供应(http://www.chemdrug.com/sell/)商,工作时间内免费技术咨询(http://www.chemdrug.com/)和指导,期待您的来电!


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CHMP2B抗体,染色质修饰蛋白2B抗体简单介绍
中文名称:染色质修饰蛋白2B抗体
英文名称:Anti-CHMP2B
产品编号:BYK-11712R
产品规格:0.1ml(100ug)、0.2ml(100ug)、1ml(1mg)
抗体来源:Rabbit or Mouse
产品性状:Lyophilized or Liquid
浓       度:1mg/1ml
亚       型:IgG
纯化方法:affinity purified by Protein A
保存条件:Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品别名:Charged multivesicular body protein 2b; CHM2B_HUMAN; CHMP2.5; CHMP2b; Chromatin modifying protein 2b; Chromatin-modifying protein 2b; DMT1; hVps2-2; Vacuolar protein sorting 2-2; VPS2 homolog B; Vacuolar protein sorting-associated protein 2-2; Vps2-2; VPS2B.


CHMP2B抗体,染色质修饰蛋白2B抗体
背景介绍:The charged multivesicular body proteins, commonly designated CHMPs, belong to the vacuolar sorting protein family and function as chromatin-modifying proteins. CHMP1-6 are all components of ESCRT (endosomal sorting complex required for transport) I, II or III complexes. These complexes are crucial for sorting endosomal articles into multivesicular bodies (MVBs), and are also required for the formation of these bodies. CHMP2B, also known as CHMP2.5 or vacuolar protein-sorting-associated protein 2-2, is a 213 amino acid cytosolic protein. Widely expressed in brain, heart, skeletal muscle, small intestine, pancreas, lung, placenta and leukocytes, CHMP2B associates directly with CHMP2A and vps4 for the disassembly of the ESCRT-III complex. Defects in the gene encoding CHMP2B have been shown to cause chromosome 3-linked frontotemporal dementia (FTD3).


CHMP2B抗体免疫组化的呈色深浅可反映抗原存在的数量,可作为定性、定位和定量的依据:
1.阳性细胞染色分布有三种类型:细胞浆、细胞核、细胞膜表面。大部分抗原见于细胞浆,可见于整个胞浆或部分胞浆
2.阳性细胞分布可分为灶型和弥漫性
3.由于细胞内含抗原量不同,所以染色强度不一。如果细胞之间染色强度相同,常提示其反应为非特异性
4.阳性细胞染色定位于单个细胞,且与阴性细胞相互交杂分布;而非特异性染色常不限于单个细胞,而是累及一片细胞。
5.切片边缘、刀痕或褶皱区域,坏死或挤压的细胞区,胶原结缔组织等,常表现为相同的阳性染色强度,不能用于判断阳性。


 该指标我公司有多抗和单抗可以选择,请添加客服QQ:1017453315索取产品说明书与报价!
 
 
染色质修饰蛋白2B抗体溶解方法:
方法1:我们的抗体(冻干粉)已经包含了0.01M PBS、1% BSA和0.1% 防腐剂(叠氮钠或庆大霉素),您只需要加入灭菌的双蒸水就行了。抗体溶解后,置于-20℃保存,*好分装后使用,避免反复冻融,可**少1年**;
方法2:也可以只加入一半体积的双蒸水,再用一半体积的甘油补足,置于-20℃保存,这样抗体不会冻,有利于抗体的稳定。
后续试验(http://www.chemdrug.com/sell/24/)时,再使用对应的缓冲液稀释成工作液,即用即配。
我们的抗体(冻干粉),在常温放置下,*少一个月**;若在-20℃下保存(推荐),*少三年**。
Antibodies are prepared with 0.01M PBS, pH 7.4 with 1% BSA and 0.1% Sodium Azide, prior to lyophilization. Currently, we offer both lyophilized and reconstituted antibodies, both resulting in final concentration of 1mg/mL. We recommend two ways to reconstitute antibodies in lyophilized form:
1) Reconstituting by directly adding 100uL of sterile, distilled water.
2) Alternatively, if glycerol does not affect the experiment, add 50uL sterile distilled water, followed by adding 50uL of glycerol.






上海研盟生物优质供应“CHMP2B抗体,染色质修饰蛋白2B抗体”,产品为*新批号,**期一年,出现任何质量问题或是实验出不了结果均可免费退换!


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