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53637-13-1

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摘 要:53637-13-1, RTECS NUMBER : PB9800000 CHEMICAL NAME : 4,7-Methanoindan, 1,2,4,5,6,7,8,8-octachloro-3a
    ◇◇◇化学鉴别信息◇◇◇
  • 【RTECS 编号】 PB9800000
  • 【化学名】 4,7-Methanoindan, 1,2,4,5,6,7,8,8-octachloro-3a,4,7,7a-tetrahydro-
  • 【CAS 登记号】 57-74-9OTHER CAS REGISTRY NOS. : 39400-80-1 53637-13-1
  • 【BEILSTEIN 参考号】 1915474
  • 【上次更新时间】 199712
  • 【引用数据项】 88
  • 【分子式】 C10-H6-Cl8
  • 【分子量】 409.76
  • 【维斯韦塞(氏)线的符号】 L C555 A IUTJ AG AG BG DG EG HG IG JG
  • 【化合物描述】 Agricultural Chemical Tumorigen Mutagen Reproductive Effector Human
  • 【别名】 * Aspon-chlordane * BELT * CD 68 * Chloordaan * Chlordan * Chlordane * Chlorindan * Chlor KIL * Chlorodane * Chlortox * Clordan * Clordano * Cortilan-neu * Dichlorochlordene * Dowchlor * ENT 9,932 * ENT 25,552-X * HCS 3260 * Kilex lindane * Kypchlor * Latka 1068 * M 140 * 4,7-Methano-1H-indene, 1,2,4,5,6,7,8,8-octachloro-2,3,3a,4,7,7a-hexahydro- * NCI-C00099 * Octachlor * Octachlorodihydrodicyclopentadiene * 1,2,4,5,6,7,8,8-Octahydro-2,3,3a,4,7,7a-hexahydro-4,7-methanoindan * 1,2,4,5,6,7,8,8-Octachlor-2,3,3a,4,7,7a-hexahydro-4,7-methanoindane * 1,2,4,5,6,7,8,8-Octachloro-2,3,3a,4,7,7a-hexahydro-4,7-methanoindene * 1,2,4,5,6,7,8,8-Octachloro-2,3,3a,4,7,7a-hexahydro-4,7-methano-1H-indene * 1,2,4,5,6,7,8,8-Octachloro-3a,4,7,7a-hexahydro-4,7-methylene indane * Octachloro-4,7-methanohydroindane * Octachloro-4,7-methanotetrahydroindane * 1,2,4,5,6,7,8,8-Octachloro-4,7-methano-3a,4,7,7a-tetrahydroindane * 1,2,4,5,6,7,8,8-Octachloor-3a,4,7,7a-tetrahydro-4,7-endo-methano-indaan * 1,2,4,5,6,7,8,8-Octachloro-3a,4,7,7a-tetrahydro-4,7-methanoindane * 1,2,4,5,6,7,10,10-Octachloro-4,7,8,9-tetrahydro-4,7-methyleneindane * 1,2,4,5,6,7,8,8-Octachlor-3a,4,7,7a-tetrahydro-4,7-endo-methano-indan * Octa-klor * Oktaterr * OMS 1437 * Ortho-klor * 1,2,4,5,6,7,8,8-Ottochloro-3a,4,7,7a-tetraidro-4,7-endo-metano-indano * RCRA waste number U036 * SD 5532 * Shell SD-5532 * Starchlor * Synklor * TAT chlor 4 * Termi-ded * Topichlor 20 * Topiclor * Topiclor 20 * Toxichlor * Unexan-koeder * Velsicol 1068
  • ◇◇◇卫生公害数据◇◇◇
    〖急性毒性数据〗
  • 【测试类型】 TDLo - Lowest published toxic dose
  • 【接触途径】 Oral
  • 【测试物种】 Human - man
  • 【剂量/时间】 3071 ug/kg
  • 【毒性作用】 Behavioral - coma Lungs, Thorax, or Respiration - dyspnea Gastrointestinal - nausea or vomiting
  • 【参考】 JTCTDW Journal of Toxicology, Clinical Toxicology. (Marcel Dekker, 270 Madison Ave., New York, NY 10016) V.19- 1982- Volume(issue)/page/year: 20,291,1983
  • 【测试类型】 LDLo - Lowest published lethal dose
  • 【接触途径】 Oral
  • 【测试物种】 Human
  • 【剂量/时间】 29 mg/kg
  • 【毒性作用】 Liver - fatty liver degeneration
  • 【参考】 CMEP** "Clinical Memoranda on Economic Poisons," U.S. Dept. HEW, Public Health Service, Communicable Disease Center, Atlanta, GA, 1956 Volume(issue)/page/year: -,1,1956
  • 【测试类型】 LDLo - Lowest published lethal dose
  • 【接触途径】 Oral
  • 【测试物种】 Human - woman
  • 【剂量/时间】 120 ug/kg
  • 【毒性作用】 Behavioral - convulsions or effect on seizure threshold Behavioral - excitement Gastrointestinal - gastritis
  • 【参考】 CMEP** "Clinical Memoranda on Economic Poisons," U.S. Dept. HEW, Public Health Service, Communicable Disease Center, Atlanta, GA, 1956 Volume(issue)/page/year: -,1,1956
  • 【测试类型】 LDLo - Lowest published lethal dose
  • 【接触途径】 Administration onto the skin
  • 【测试物种】 Human
  • 【剂量/时间】 428 mg/kg
  • 【毒性作用】 Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia
  • 【参考】 34ZIAG "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969 Volume(issue)/page/year: -,648,1969
  • 【测试类型】 LDLo - Lowest published lethal dose
  • 【接触途径】 Unreported
  • 【测试物种】 Human - man
  • 【剂量/时间】 118 mg/kg
  • 【毒性作用】 Details of toxic effects not reported other than lethal dose value
  • 【参考】 85DCAI "Poisoning; Toxicology, Symptoms, Treatments," 2nd ed., Arena, J.M., Springfield, IL, C.C. Thomas, 1970 Volume(issue)/page/year: 2,73,1970
  • 【测试类型】 LD50 - Lethal dose, 50 percent kill
  • 【接触途径】 Oral
  • 【测试物种】 Rodent - rat
  • 【剂量/时间】 200 mg/kg
  • 【毒性作用】 Details of toxic effects not reported other than lethal dose value
  • 【参考】 ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 17,614,1967
  • 【测试类型】 LD50 - Lethal dose, 50 percent kill
  • 【接触途径】 Administration onto the skin
  • 【测试物种】 Rodent - rat
  • 【剂量/时间】 690 mg/kg
  • 【毒性作用】 Details of toxic effects not reported other than lethal dose value
  • 【参考】 JAVMA4 Journal of the American Veterinary Medical Association. (American Veterinary Medical Assoc., 930 N. Meacham Rd., Schaumburg, IL 60196) V.48- 1915- Volume(issue)/page/year: 157,1835,1970
  • 【测试类型】 LD50 - Lethal dose, 50 percent kill
  • 【接触途径】 Intraperitoneal
  • 【测试物种】 Rodent - rat
  • 【剂量/时间】 343 mg/kg
  • 【毒性作用】 Details of toxic effects not reported other than lethal dose value
  • 【参考】 TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 32,443,1975
  • 【测试类型】 LD50 - Lethal dose, 50 percent kill
  • 【接触途径】 Oral
  • 【测试物种】 Rodent - mouse
  • 【剂量/时间】 145 mg/kg
  • 【毒性作用】 Details of toxic effects not reported other than lethal dose value
  • 【参考】 ARSIM* Agricultural Research Service, USDA Information Memorandum. (Beltsville, MD 20705) Volume(issue)/page/year: 20,19,1966
  • 【测试类型】 LDLo - Lowest published lethal dose
  • 【接触途径】 Intraperitoneal
  • 【测试物种】 Rodent - mouse
  • 【剂量/时间】 240 mg/kg
  • 【毒性作用】 Details of toxic effects not reported other than lethal dose value
  • 【参考】 TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 23,288,1972
  • 【测试类型】 LD50 - Lethal dose, 50 percent kill
  • 【接触途径】 Intravenous
  • 【测试物种】 Rodent - mouse
  • 【剂量/时间】 100 mg/kg
  • 【毒性作用】 Details of toxic effects not reported other than lethal dose value
  • 【参考】 CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#04876
  • 【测试类型】 LC50 - Lethal concentration, 50 percent kill
  • 【接触途径】 Inhalation
  • 【测试物种】 Mammal - cat
  • 【剂量/时间】 100 mg/m3/4H
  • 【毒性作用】 Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Behavioral - excitement
  • 【参考】 GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 8(4),30,1964
  • 【测试类型】 LD50 - Lethal dose, 50 percent kill
  • 【接触途径】 Oral
  • 【测试物种】 Rodent - rabbit
  • 【剂量/时间】 100 mg/kg
  • 【毒性作用】 Details of toxic effects not reported other than lethal dose value
  • 【参考】 PCOC** Pesticide Chemicals Official Compendium, Association of the American Pesticide Control Officials, Inc., 1966. (Topeka, KS) Volume(issue)/page/year: -,226,1966
  • 【测试类型】 LD50 - Lethal dose, 50 percent kill
  • 【接触途径】 Administration onto the skin
  • 【测试物种】 Rodent - rabbit
  • 【剂量/时间】 780 mg/kg
  • 【毒性作用】 Details of toxic effects not reported other than lethal dose value
  • 【参考】 85DPAN "Wirksubstanzen der Pflanzenschutz und Schadlingsbekampfungsmittel," Perkow, W., Berlin, Verlag Paul Parey, 1971-1976 Volume(issue)/page/year: -,-,1971/1976
  • 【测试类型】 LDLo - Lowest published lethal dose
  • 【接触途径】 Intravenous
  • 【测试物种】 Rodent - rabbit
  • 【剂量/时间】 10 mg/kg
  • 【毒性作用】 Details of toxic effects not reported other than lethal dose value
  • 【参考】 AIHOAX Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.1-2(3), 1950. For publisher information, see AEHLAU. Volume(issue)/page/year: 1,13,1950
  • 【测试类型】 LD50 - Lethal dose, 50 percent kill
  • 【接触途径】 Oral
  • 【测试物种】 Rodent - hamster
  • 【剂量/时间】 1720 mg/kg
  • 【毒性作用】 Details of toxic effects not reported other than lethal dose value
  • 【参考】 EJTXAZ European Journal of Toxicology and Environmental Hygiene. (Paris, France) V.7-9, 1974-76. For publisher information, see TOERD9. Volume(issue)/page/year: 7,159,1974
  • 【测试类型】 LD50 - Lethal dose, 50 percent kill
  • 【接触途径】 Oral
  • 【测试物种】 Bird - chicken
  • 【剂量/时间】 220 mg/kg
  • 【毒性作用】 Details of toxic effects not reported other than lethal dose value
  • 【参考】 PCOC** Pesticide Chemicals Official Compendium, Association of the American Pesticide Control Officials, Inc., 1966. (Topeka, KS) Volume(issue)/page/year: -,226,1966
  • 【测试类型】 LD50 - Lethal dose, 50 percent kill
  • 【接触途径】 Oral
  • 【测试物种】 Bird - duck
  • 【剂量/时间】 1200 mg/kg
  • 【毒性作用】 Details of toxic effects not reported other than lethal dose value
  • 【参考】 DOEAAH Down to Earth. (Dow Chemical USA, Agricultural Products Dept., Midland, MI 48640) V.1- 1945- Volume(issue)/page/year: 35,25,1979
  • 【测试类型】 LD50 - Lethal dose, 50 percent kill
  • 【接触途径】 Oral
  • 【测试物种】 Mammal - domestic
  • 【剂量/时间】 50 mg/kg
  • 【毒性作用】 Details of toxic effects not reported other than lethal dose value
  • 【参考】 YKYUA6 Yakkyoku. Pharmacy. (Nanzando, 4-1-11, Yushima, Bunkyo-ku, Tokyo, Japan) V.1- 1950- Volume(issue)/page/year: 32,471,1981
  • 【测试类型】 LD50 - Lethal dose, 50 percent kill
  • 【接触途径】 Oral
  • 【测试物种】 Mammal - species unspecified
  • 【剂量/时间】 180 mg/kg
  • 【毒性作用】 Details of toxic effects not reported other than lethal dose value
  • 【参考】 PCOC** Pesticide Chemicals Official Compendium, Association of the American Pesticide Control Officials, Inc., 1966. (Topeka, KS) Volume(issue)/page/year: -,226,1966
  • 【测试类型】 LC50 - Lethal concentration, 50 percent kill
  • 【接触途径】 Inhalation
  • 【测试物种】 Mammal - species unspecified
  • 【剂量/时间】 >20 gm/m3/4H
  • 【毒性作用】 Details of toxic effects not reported other than lethal dose value
  • 【参考】 PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,139,1991
  • 〖其他多剂量毒性数据〗
  • 【测试类型】 TDLo - Lowest published toxic dose
  • 【接触途径】 Oral
  • 【测试物种】 Rodent - rat
  • 【剂量/时间】 410 mg/kg/39W-C
  • 【毒性作用】 Liver - other changes
  • 【参考】 AMPLAO AMA Archives of Pathology. (Chicago, IL) V.50(4)-69, 1950-60. For publisher information, see APLMAS. Volume(issue)/page/year: 64,614,1957
  • 【测试类型】 TCLo - Lowest published toxic concentration
  • 【接触途径】 Inhalation
  • 【测试物种】 Rodent - rat
  • 【剂量/时间】 28200 ug/m3/8H/28D-I
  • 【毒性作用】 Liver - changes in liver weight Kidney, Ureter, Bladder - changes in bladder weight Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
  • 【参考】 JTEHD6 Journal of Toxicology and Environmental Health. (Hemisphere Pub., 1025 Vermont Ave., NW, Washington, DC 20005) V.1- 1975/76- Volume(issue)/page/year: 28,327,1989
  • 【测试类型】 TDLo - Lowest published toxic dose
  • 【接触途径】 Oral
  • 【测试物种】 Rodent - rat
  • 【剂量/时间】 660 mg/kg/15D-I
  • 【毒性作用】 Behavioral - convulsions or effect on seizure threshold Related to Chronic Data - death
  • 【参考】 AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU. Volume(issue)/page/year: 7,197,1953
  • 【测试类型】 TDLo - Lowest published toxic dose
  • 【接触途径】 Oral
  • 【测试物种】 Rodent - rat
  • 【剂量/时间】 6512 mg/kg/58W-I
  • 【毒性作用】 Liver - changes in liver weight Nutritional and Gross Metabolic - weight loss or decreased weight gain
  • 【参考】 AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU. Volume(issue)/page/year: 7,197,1953
  • 【测试类型】 TDLo - Lowest published toxic dose
  • 【接触途径】 Oral
  • 【测试物种】 Rodent - rat
  • 【剂量/时间】 5475 mg/kg/2Y-C
  • 【毒性作用】 Liver - hepatitis (hepatocellular necrosis), zonal Liver - changes in liver weight Related to Chronic Data - death
  • 【参考】 AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU. Volume(issue)/page/year: 6,357,1952
  • 【测试类型】 TCLo - Lowest published toxic concentration
  • 【接触途径】 Inhalation
  • 【测试物种】 Rodent - rat
  • 【剂量/时间】 10 mg/m3/8H/90D-I
  • 【毒性作用】 Liver - changes in liver weight Kidney, Ureter, Bladder - changes in bladder weight Nutritional and Gross Metabolic - changes in calcium
  • 【参考】 JTEHD6 Journal of Toxicology and Environmental Health. (Hemisphere Pub., 1025 Vermont Ave., NW, Washington, DC 20005) V.1- 1975/76- Volume(issue)/page/year: 28,327,1989
  • 【测试类型】 TDLo - Lowest published toxic dose
  • 【接触途径】 Oral
  • 【测试物种】 Rodent - rat
  • 【剂量/时间】 504 mg/kg/12W-C
  • 【毒性作用】 Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase
  • 【参考】 APTOD9 Abstracts of Papers, Society of Toxicology. Annual Meetings. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) Volume(issue)/page/year: 19,A99,1980
  • 〖致肿瘤数据数据〗
  • 【测试类型】 TDLo - Lowest published toxic dose
  • 【接触途径】 Oral
  • 【测试物种】 Rodent - mouse
  • 【剂量/时间】 2020 mg/kg/80W-C
  • 【毒性作用】 Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors
  • 【参考】 NCITR* National Cancer Institute Carcinogenesis Technical Report Series. (Bethesda, MD) No.0-205. For publisher information, see NTPTR*. Volume(issue)/page/year: NCI-TR-8,1977
  • 【测试类型】 TD - Toxic dose (other than lowest)
  • 【接触途径】 Oral
  • 【测试物种】 Rodent - mouse
  • 【剂量/时间】 3780 mg/kg/80W-C
  • 【毒性作用】 Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors
  • 【参考】 NCITR* National Cancer Institute Carcinogenesis Technical Report Series. (Bethesda, MD) No.0-205. For publisher information, see NTPTR*. Volume(issue)/page/year: NCI-TR-8,1977
  • 〖繁殖数据〗
  • 【测试类型】 TDLo - Lowest published toxic dose
  • 【接触途径】 Oral
  • 【测试物种】 Rodent - mouseDOSE : 3360 ug/kgSEX/DURATION : female 1-21 day(s) after conception
  • 【毒性作用】 Reproductive - Specific Developmental Abnormalities - endocrine system Reproductive - Effects on Newborn - biochemical and metabolic
  • 【参考】 JEPTDQ Journal of Environmental Pathology and Toxicology. (Park Forest South, IL) V.1-5(3), 1977-81(?). For publisher information, see JEPOEC. Volume(issue)/page/year: 2(2),357,1978
  • 【测试类型】 TDLo - Lowest published toxic dose
  • 【接触途径】 Oral
  • 【测试物种】 Rodent - mouseDOSE : 152 mg/kgSEX/DURATION : female 1-19 day(s) after conception
  • 【毒性作用】 Reproductive - Specific Developmental Abnormalities - immune and reticuloendothelial system
  • 【参考】 TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 62,402,1982
  • 【测试类型】 TDLo - Lowest published toxic dose
  • 【接触途径】 Oral
  • 【测试物种】 Rodent - mouseDOSE : 7 mg/kgSEX/DURATION : female 15-21 day(s) after conception
  • 【毒性作用】 Reproductive - Effects on Newborn - behavioral
  • 【参考】 BJPCBM British Journal of Pharmacology. (Macmillan Press Ltd., Houndmills, Basingstoke, Hants. RG21 2XS, UK) V.34- 1968- Volume(issue)/page/year: 49,311,1973
  • 【测试类型】 TDLo - Lowest published toxic dose
  • 【接触途径】 Oral
  • 【测试物种】 Rodent - mouseDOSE : 3040 ug/kgSEX/DURATION : female 1-19 day(s) after conception
  • 【毒性作用】 Reproductive - Effects on Newborn - biochemical and metabolic
  • 【参考】 ENVRAL Environmental Research. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1967- Volume(issue)/page/year: 35,204,1984
  • 【测试类型】 TDLo - Lowest published toxic dose
  • 【接触途径】 Unreported
  • 【测试物种】 Rodent - mouseDOSE : 168 mg/kgSEX/DURATION : female 1-21 day(s) after conception
  • 【毒性作用】 Reproductive - Effects on Newborn - delayed effects
  • 【参考】 APTOD9 Abstracts of Papers, Society of Toxicology. Annual Meetings. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) Volume(issue)/page/year: 19,A18,1980
  • 【测试类型】 TDLo - Lowest published toxic dose
  • 【接触途径】 Unreported
  • 【测试物种】 Rodent - mouseDOSE : 168 mg/kgSEX/DURATION : female 1-21 day(s) after conception
  • 【毒性作用】 Reproductive - Specific Developmental Abnormalities - immune and reticuloendothelial system
  • 【参考】 TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 19,23A,1979
    〖致突变数据〗
  • 【测试类型】 Phage inhibition capacityTEST SYSTEM : Bacteria - Escherichia coli
  • 【剂量/时间】 3050 umol/L
  • 【参考】 MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 182,193,1987
  • 【测试类型】 Sister chromatid exchange
  • 【接触途径】 Multiple routesTEST SYSTEM : Fish - not otherwise specified
  • 【剂量/时间】 54 pmol/L
  • 【参考】 MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 118,61,1983
  • 【测试类型】 Unscheduled DNA synthesisTEST SYSTEM : Human Fibroblast
  • 【剂量/时间】 1 umol/L
  • 【参考】 MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 42,161,1977
  • 【测试类型】 Sister chromatid exchangeTEST SYSTEM : Human Lymphocyte
  • 【剂量/时间】 10 umol/L
  • 【参考】 ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974- Volume(issue)/page/year: 52,221,1983
  • 【测试类型】 Morphological transformation
  • 【接触途径】 OralTEST SYSTEM : Rodent - rat
  • 【剂量/时间】 1260 mg/kg/6W
  • 【参考】 CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 9,387,1988
  • 【测试类型】 Mutation test systems - not otherwise specified
  • 【接触途径】 OralTEST SYSTEM : Rodent - mouse
  • 【剂量/时间】 35 mg/kg
  • 【参考】 MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 343,157,1995
  • 【测试类型】 Cytogenetic analysis
  • 【接触途径】 OralTEST SYSTEM : Rodent - mouse
  • 【剂量/时间】 10 mg/kg
  • 【参考】 MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 301,33,1993
  • 【测试类型】 Mutation in mammalian somatic cellsTEST SYSTEM : Rodent - hamster Lung
  • 【剂量/时间】 10 umol/L
  • 【参考】 CBINA8 Chemico-Biological Interactions. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1969- Volume(issue)/page/year: 19,369,1977
  • ◇◇◇综述◇◇◇
  • ACGIH TLV-Animal carcinogen DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 ACGIH TLV-TWA 0.5 mg/m3 (skin) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 IARC Cancer Review:Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 20,45,1979 IARC Cancer Review:Animal Limited Evidence IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,146,1987 IARC Cancer Review:Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 53,115,1991 IARC Cancer Review:Human Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 20,45,1979 IARC Cancer Review:Human Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 53,115,1991 IARC Cancer Review:Group 2B IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 53,115,1991 TOXICOLOGY REVIEW CNDQA8 Cahiers de Nutrition et de Dietetique. (Editions Meteore, 42, rue du Louvre, 75001 Paris, France) V.1- 1966- Volume(issue)/page/year: 10(3),43,1975 TOXICOLOGY REVIEW RREVAH Residue Reviews. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1962- Volume(issue)/page/year: 56,107,1975 TOXICOLOGY REVIEW BNYMAM Bulletin of the New York Academy of Medicine. (New York Academy of Medicine, 2 E. 103rd St., New York, NY 10029) Ser 2: V.1- 1925- Volume(issue)/page/year: 54,413,1978 TOXICOLOGY REVIEW CTOXAO Clinical Toxicology. (New York, NY) V.1-18, 1968-81. For publisher information, see JTCTDW. Volume(issue)/page/year: 13,231,1978
  • ◇◇◇美国标准和规章◇◇◇
  • EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 MSHA STANDARD-air:TWA 0.5 mg/m3 (skin) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: 3,44,1971 OSHA PEL (Gen Indu):8H TWA 0.5 mg/m3 (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994 OSHA PEL (Construc):8H TWA 0.5 mg/m3 (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA PEL (Shipyard):8H TWA 0.5 mg/m3 (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 OSHA PEL (Fed Cont):8H TWA 0.5 mg/m3 (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994
  • ◇◇◇职业接触限量◇◇◇
  • OEL-ARAB Republic of Egypt:TWA 0.5 mg/m3;Skin JAN 1993 OEL-AUSTRALIA:TWA 0.5 mg/m3;STEL 2 mg/m3;Skin;Carcinogen JAN 1993 OEL-AUSTRIA:TWA 0.5 mg/m3;Skin JAN 1993 OEL-BELGIUM:TWA 0.5 mg/m3;STEL 2 mg/m3;Skin JAN 1993 OEL-DENMARK:TWA 0.5 mg/m3;Skin;Carcinogen JAN 1993 OEL-FINLAND;Carcinogen JAN 1993 OEL-FRANCE:TWA 0.5 mg/m3;Skin JAN 1993 OEL-GERMANY:TWA 0.5 mg/m3;Skin;Carcinogen JAN 1993 OEL-INDIA:TWA 0.5 mg/m3;STEL 2 mg/m3;Skin JAN 1993 OEL-THE NETHERLANDS:TWA 0.5 mg/m3;Skin JAN 1993 OEL-THE PHILIPPINES:TWA 0.5 mg/m3;Skin JAN 1993 OEL-RUSSIA:STEL 0.01 mg/m3;Skin JAN 1993 OEL-SWITZERLAND:TWA 0.5 mg/m3;Skin JAN 1993 OEL-THAILAND:TWA 0.5 mg/m3 JAN 1993 OEL-TURKEY:TWA 0.5 mg/m3;Skin JAN 1993 OEL-UNITED KINGDOM:TWA 0.5 mg/m3;STEL 2 mg/m3;Skin JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV
  • ◇◇◇NIOSH 标准发展和监测数据◇◇◇
    NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO CHLORDANE-air:10H CA TWA 0.5 mg/m3 (Sk)
  • 【参考】 NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992
  • ◇◇◇在美国的情况◇◇◇
  • ATSDR TOXICOLOGY PROFILE NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: PB/90/168709/AS EPA TSCA Section 8(d) unpublished health/safety studies On EPA IRIS database EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998 NIOSH Analytical Method, 1994: Chlordane, 5510 NCI Carcinogenesis Bioassay (feed);clear evidence:mouse NCITR* National Cancer Institute Carcinogenesis Technical Report Series. (Bethesda, MD) No.0-205. For publisher information, see NTPTR*. Volume(issue)/page/year: NCI-TR-8,77 NCI Carcinogenesis Bioassay (feed);no evidence:rat NCITR* National Cancer Institute Carcinogenesis Technical Report Series. (Bethesda, MD) No.0-205. For publisher information, see NTPTR*. Volume(issue)/page/year: NCI-TR-8,77
  • ◇◇◇全部数据完毕◇◇◇
 
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