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1327-53-3

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摘 要:1327-53-3, RTECS NUMBER : CG3325000 CHEMICAL NAME : Arsenic trioxide CAS REGISTRY NUMBER : 1327-53-3
    ◇◇◇化学鉴别信息◇◇◇
  • 【RTECS 编号】 CG3325000
  • 【化学名】 Arsenic trioxide
  • 【CAS 登记号】 1327-53-3
  • 【上次更新时间】 199712
  • 【引用数据项】 81
  • 【分子式】 As2-O3
  • 【分子量】 197.84
  • 【维斯韦塞(氏)线的符号】 AS2 O3
  • 【化合物描述】 Agricultural Chemical Tumorigen Drug Mutagen Reproductive Effector Human
  • 【别名】 * Acide arsenieux * Anhydride arsenieux * Arsenic blanc * Arsenic oxide * Arsenic(III) oxide * Arsenic sesquioxide * Arsenic trioxide * Arsenicum album * Arsenigen saure * Arsenious acid * Arsenious oxide * Arsenious trioxide * Arsenite * Arsenolite * Arsenous acid * Arsenous acid anhydride * Arsenous anhydride * Arsenous oxide * Arsenous oxide anhydride * Arsentrioxide * Arsodent * Claudelite * Claudetite * Crude arsenic * Diarsenic trioxide * RCRA waste number P012 * White arsenic
  • ◇◇◇卫生公害数据◇◇◇
    〖急性毒性数据〗
  • 【测试类型】 LDLo - Lowest published lethal dose
  • 【接触途径】 Oral
  • 【测试物种】 Human - man
  • 【剂量/时间】 29 mg/kg
  • 【毒性作用】 Behavioral - sleep Behavioral - muscle weakness Gastrointestinal - hypermotility, diarrhea
  • 【参考】 AEMED3 Annals of Emergency Medicine. (American College of Emergency Physicians, 1125 Executive Circle, Irving, TX 75038) Volume(issue)/page/year: 16,702,1987
  • 【测试类型】 LDLo - Lowest published lethal dose
  • 【接触途径】 Oral
  • 【测试物种】 Human - man
  • 【剂量/时间】 286 mg/kg
  • 【毒性作用】 Cardiac - arrhythmias (including changes in conduction) Liver - liver function tests impaired Musculoskeletal - other changes
  • 【参考】 JTCTDW Journal of Toxicology, Clinical Toxicology. (Marcel Dekker, 270 Madison Ave., New York, NY 10016) V.19- 1982- Volume(issue)/page/year: 29,45,1991
  • 【测试类型】 LDLo - Lowest published lethal dose
  • 【接触途径】 Oral
  • 【测试物种】 Human
  • 【剂量/时间】 1429 ug/kg
  • 【毒性作用】 Details of toxic effects not reported other than lethal dose value
  • 【参考】 YKYUA6 Yakkyoku. Pharmacy. (Nanzando, 4-1-11, Yushima, Bunkyo-ku, Tokyo, Japan) V.1- 1950- Volume(issue)/page/year: 31,1247,1980
  • 【测试类型】 LDLo - Lowest published lethal dose
  • 【接触途径】 Oral
  • 【测试物种】 Human - man
  • 【剂量/时间】 2857 mg/kg
  • 【毒性作用】 Behavioral - coma Liver - fatty liver degeneration Kidney, Ureter, Bladder - renal function tests depressed
  • 【参考】 JTCTDW Journal of Toxicology, Clinical Toxicology. (Marcel Dekker, 270 Madison Ave., New York, NY 10016) V.19- 1982- Volume(issue)/page/year: 29,131,1991
  • 【测试类型】 LDLo - Lowest published lethal dose
  • 【接触途径】 Unreported
  • 【测试物种】 Human - man
  • 【剂量/时间】 2941 ug/kg
  • 【毒性作用】 Details of toxic effects not reported other than lethal dose value
  • 【参考】 85DCAI "Poisoning; Toxicology, Symptoms, Treatments," 2nd ed., Arena, J.M., Springfield, IL, C.C. Thomas, 1970 Volume(issue)/page/year: 2,73,1970
  • 【测试类型】 LD50 - Lethal dose, 50 percent kill
  • 【接触途径】 Oral
  • 【测试物种】 Rodent - rat
  • 【剂量/时间】 14600 ug/kg
  • 【毒性作用】 Details of toxic effects not reported other than lethal dose value
  • 【参考】 GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 52(1),21,1987
  • 【测试类型】 LD50 - Lethal dose, 50 percent kill
  • 【接触途径】 Intraperitoneal
  • 【测试物种】 Rodent - rat
  • 【剂量/时间】 871 mg/kg
  • 【毒性作用】 Details of toxic effects not reported other than lethal dose value
  • 【参考】 GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 19(3),30,1975
  • 【测试类型】 LDLo - Lowest published lethal dose
  • 【接触途径】 Subcutaneous
  • 【测试物种】 Rodent - rat
  • 【剂量/时间】 8 mg/kg
  • 【毒性作用】 Skin and Appendages - corrosive (after topical exposure)
  • 【参考】 JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 19,337,1922
  • 【测试类型】 LDLo - Lowest published lethal dose
  • 【接触途径】 Unreported
  • 【测试物种】 Rodent - rat
  • 【剂量/时间】 8 mg/kg
  • 【毒性作用】 Details of toxic effects not reported other than lethal dose value
  • 【参考】 BIZEA2 Biochemische Zeitschrift. (Berlin, Ger.) V.1-346, 1906-67. For publisher information, see EJBCAI. Volume(issue)/page/year: 184,360,1927
  • 【测试类型】 LD50 - Lethal dose, 50 percent kill
  • 【接触途径】 Oral
  • 【测试物种】 Rodent - mouse
  • 【剂量/时间】 31500 ug/kg
  • 【毒性作用】 Details of toxic effects not reported other than lethal dose value
  • 【参考】 CHYCDW Zhonghua Yufangyixue Zazhi. Chinese Journal of Preventive Medicine. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) Beginning history not known. Volume(issue)/page/year: 14,86,1980
  • 【测试类型】 LD50 - Lethal dose, 50 percent kill
  • 【接触途径】 Subcutaneous
  • 【测试物种】 Rodent - mouse
  • 【剂量/时间】 9800 ug/kg
  • 【毒性作用】 Details of toxic effects not reported other than lethal dose value
  • 【参考】 PSEBAA Proceedings of the Society for Experimental Biology and Medicine. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04- Volume(issue)/page/year: 78,392,1951
  • 【测试类型】 LD50 - Lethal dose, 50 percent kill
  • 【接触途径】 Intravenous
  • 【测试物种】 Rodent - mouse
  • 【剂量/时间】 10700 ug/kg
  • 【毒性作用】 Details of toxic effects not reported other than lethal dose value
  • 【参考】 PSEBAA Proceedings of the Society for Experimental Biology and Medicine. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04- Volume(issue)/page/year: 78,392,1951
  • 【测试类型】 LDLo - Lowest published lethal dose
  • 【接触途径】 Oral
  • 【测试物种】 Mammal - dog
  • 【剂量/时间】 10 mg/kg
  • 【毒性作用】 Details of toxic effects not reported other than lethal dose value
  • 【参考】 HBAMAK "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." (Leipzig, Ger. Dem. Rep.) Volume(issue)/page/year: 4,1306,1935
  • 【测试类型】 LDLo - Lowest published lethal dose
  • 【接触途径】 Intradermal
  • 【测试物种】 Mammal - dog
  • 【剂量/时间】 2 mg/kg
  • 【毒性作用】 Details of toxic effects not reported other than lethal dose value
  • 【参考】 HBAMAK "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." (Leipzig, Ger. Dem. Rep.) Volume(issue)/page/year: 4,1306,1935
  • 【测试类型】 LD50 - Lethal dose, 50 percent kill
  • 【接触途径】 Oral
  • 【测试物种】 Rodent - rabbit
  • 【剂量/时间】 20190 ug/kg
  • 【毒性作用】 Details of toxic effects not reported other than lethal dose value
  • 【参考】 CHYCDW Zhonghua Yufangyixue Zazhi. Chinese Journal of Preventive Medicine. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) Beginning history not known. Volume(issue)/page/year: 22,284,1988
  • 【测试类型】 LDLo - Lowest published lethal dose
  • 【接触途径】 Intravenous
  • 【测试物种】 Rodent - rabbit
  • 【剂量/时间】 10560 ug/kg
  • 【毒性作用】 Lungs, Thorax, or Respiration - other changes Gastrointestinal - hypermotility, diarrhea Blood - other changes
  • 【参考】 BIZEA2 Biochemische Zeitschrift. (Berlin, Ger.) V.1-346, 1906-67. For publisher information, see EJBCAI. Volume(issue)/page/year: 70,144,1915
  • 【测试类型】 LDLo - Lowest published lethal dose
  • 【接触途径】 Intradermal
  • 【测试物种】 Bird - pigeon
  • 【剂量/时间】 100 mg/kg
  • 【毒性作用】 Details of toxic effects not reported other than lethal dose value
  • 【参考】 HBAMAK "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." (Leipzig, Ger. Dem. Rep.) Volume(issue)/page/year: 4,1306,1935
  • 【测试类型】 LDLo - Lowest published lethal dose
  • 【接触途径】 Intradermal
  • 【测试物种】 Bird - chicken
  • 【剂量/时间】 13 mg/kg
  • 【毒性作用】 Details of toxic effects not reported other than lethal dose value
  • 【参考】 HBAMAK "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." (Leipzig, Ger. Dem. Rep.) Volume(issue)/page/year: 4,1306,1935
  • 【测试类型】 LDLo - Lowest published lethal dose
  • 【接触途径】 Oral
  • 【测试物种】 Mammal - cattle
  • 【剂量/时间】 30 mg/kg
  • 【毒性作用】 Details of toxic effects not reported other than lethal dose value
  • 【参考】 HBAMAK "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." (Leipzig, Ger. Dem. Rep.) Volume(issue)/page/year: 4,1306,1935
  • 〖其他多剂量毒性数据〗
  • 【测试类型】 TDLo - Lowest published toxic dose
  • 【接触途径】 Oral
  • 【测试物种】 Rodent - rat
  • 【剂量/时间】 900 mg/kg/15W-I
  • 【毒性作用】 Behavioral - changes in motor activity (specific assay) Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death
  • 【参考】 NTOTDY Neurobehavioral Toxicology and Teratology. (Fayetteville, NY) V.3-8, 1981-86. For publisher information, see NETEEC. Volume(issue)/page/year: 5,91,1983
  • 【测试类型】 TDLo - Lowest published toxic dose
  • 【接触途径】 Oral
  • 【测试物种】 Rodent - rat
  • 【剂量/时间】 350 ug/kg/30D-I
  • 【毒性作用】 Kidney, Ureter, Bladder - other changes in urine composition Nutritional and Gross Metabolic - changes in sodium Nutritional and Gross Metabolic - changes in potassium
  • 【参考】 GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 52(1),21,1987
  • 【测试类型】 TCLo - Lowest published toxic concentration
  • 【接触途径】 Inhalation
  • 【测试物种】 Rodent - rat
  • 【剂量/时间】 31 ug/m3/24H/22W-C
  • 【毒性作用】 Brain and Coverings - recordings from specific areas of CNS Blood - other changes
  • 【参考】 GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 47(1),6,1982
  • 【测试类型】 TCLo - Lowest published toxic concentration
  • 【接触途径】 Inhalation
  • 【测试物种】 Rodent - rat
  • 【剂量/时间】 500 ug/m3/24H/33D-C
  • 【毒性作用】 Brain and Coverings - recordings from specific areas of CNS Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase
  • 【参考】 GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 47(11),74,1982
  • 〖致肿瘤数据数据〗
  • 【测试类型】 TDLo - Lowest published toxic dose
  • 【接触途径】 Intratracheal
  • 【测试物种】 Rodent - rat
  • 【剂量/时间】 16 mg/kg/15W-I
  • 【毒性作用】 Tumorigenic - equivocal tumorigenic agent by RTECS criteria Lungs, Thorax, or Respiration - tumors
  • 【参考】 EVHPAZ EHP, Environmental Health Perspectives. (U.S. Government Printing Office, Supt of Documents, Washington, DC 20402) No.1- 1972- Volume(issue)/page/year: 19,191,1977
  • 【测试类型】 TDLo - Lowest published toxic dose
  • 【接触途径】 Intratracheal
  • 【测试物种】 Rodent - hamster
  • 【剂量/时间】 45 mg/kg/15W-I
  • 【毒性作用】 Tumorigenic - neoplastic by RTECS criteria Lungs, Thorax, or Respiration - tumors
  • 【参考】 ATSUDG Archives of Toxicology, Supplement. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) No.1- 1978- Volume(issue)/page/year: 7,403,1984
  • 【测试类型】 TD - Toxic dose (other than lowest)
  • 【接触途径】 Intratracheal
  • 【测试物种】 Rodent - rat
  • 【剂量/时间】 75 mg/kg/15W-I
  • 【毒性作用】 Tumorigenic - equivocal tumorigenic agent by RTECS criteria Lungs, Thorax, or Respiration - tumors
  • 【参考】 FKIZA4 Fukuoka Igaku Zasshi. (c/o Kyushu Daigaku Igakubu, Tatekasu, Fukuoka-shi, Fukuoka, Japan) V.33- 1940- Volume(issue)/page/year: 71,19,1980
  • 【测试类型】 TD - Toxic dose (other than lowest)
  • 【接触途径】 Intratracheal
  • 【测试物种】 Rodent - hamster
  • 【剂量/时间】 40 mg/kg/15W-I
  • 【毒性作用】 Tumorigenic - equivocal tumorigenic agent by RTECS criteria Lungs, Thorax, or Respiration - tumors
  • 【参考】 CALEDQ Cancer Letters (Shannon, Ireland). (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1975- Volume(issue)/page/year: 21,141,1983
  • 【测试类型】 TD - Toxic dose (other than lowest)
  • 【接触途径】 Intratracheal
  • 【测试物种】 Rodent - hamster
  • 【剂量/时间】 55450 ug/kg/15W-I
  • 【毒性作用】 Tumorigenic - neoplastic by RTECS criteria Lungs, Thorax, or Respiration - tumors
  • 【参考】 CALEDQ Cancer Letters (Shannon, Ireland). (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1975- Volume(issue)/page/year: 21,141,1983
  • 【测试类型】 TD - Toxic dose (other than lowest)
  • 【接触途径】 Intratracheal
  • 【测试物种】 Rodent - rat
  • 【剂量/时间】 167 mg/kg/15W-I
  • 【毒性作用】 Tumorigenic - equivocal tumorigenic agent by RTECS criteria Lungs, Thorax, or Respiration - tumors
  • 【参考】 SAIGBL Sangyo Igaku. Japanese Journal of Industrial Health. (Nippon Sangyo Eisei Igakkai, Kosu Eisei Bldg., 1-29-8, Shinjuku, Shinjuku-ku, Tokyo 160, Japan) V.1- 1959- Volume(issue)/page/year: 20,230,1978
  • 【测试类型】 TD - Toxic dose (other than lowest)
  • 【接触途径】 Intratracheal
  • 【测试物种】 Rodent - hamster
  • 【剂量/时间】 39608 ug/kg/24W-I
  • 【毒性作用】 Tumorigenic - equivocal tumorigenic agent by RTECS criteria Lungs, Thorax, or Respiration - tumors
  • 【参考】 JOUOD4 Journal of UOEH (University of Occupational and Environmental Health). (Univ. of Occupational and Environmental Health, 1-1 Iseigaoka, Yahata-nishi-ku, Kitakyushu 807, Japan) V.1- 1979- Volume(issue)/page/year: 5(Suppl),109,1983
  • 【测试类型】 TD - Toxic dose (other than lowest)
  • 【接触途径】 Intratracheal
  • 【测试物种】 Rodent - hamster
  • 【剂量/时间】 55456 ug/kg/24W-I
  • 【毒性作用】 Tumorigenic - equivocal tumorigenic agent by RTECS criteria Lungs, Thorax, or Respiration - tumors
  • 【参考】 JOUOD4 Journal of UOEH (University of Occupational and Environmental Health). (Univ. of Occupational and Environmental Health, 1-1 Iseigaoka, Yahata-nishi-ku, Kitakyushu 807, Japan) V.1- 1979- Volume(issue)/page/year: 5(Suppl),109,1983
  • 【测试类型】 TD - Toxic dose (other than lowest)
  • 【接触途径】 Intratracheal
  • 【测试物种】 Rodent - hamster
  • 【剂量/时间】 30 mg/kg/15W-I
  • 【毒性作用】 Tumorigenic - neoplastic by RTECS criteria Lungs, Thorax, or Respiration - tumors
  • 【参考】 SAIGBL Sangyo Igaku. Japanese Journal of Industrial Health. (Nippon Sangyo Eisei Igakkai, Kosu Eisei Bldg., 1-29-8, Shinjuku, Shinjuku-ku, Tokyo 160, Japan) V.1- 1959- Volume(issue)/page/year: 24,523,1982
  • 〖繁殖数据〗
  • 【测试类型】 TDLo - Lowest published toxic dose
  • 【接触途径】 Oral
  • 【测试物种】 Human - womanDOSE : 600 mg/kgSEX/DURATION : female 30 week(s) after conception
  • 【毒性作用】 Reproductive - Effects on Newborn - Apgar score (human only) Reproductive - Effects on Newborn - other neonatal measures or effects
  • 【参考】 AJDCAI American Journal of Diseases of Children. (AMA, 535 N. Dearborn St., Chicago, IL 60610) V.1-80(3), 1911-50; V.100- 1960- Volume(issue)/page/year: 117,328,1969
  • 【测试类型】 TDLo - Lowest published toxic dose
  • 【接触途径】 Oral
  • 【测试物种】 Rodent - mouseDOSE : 224 mg/kgSEX/DURATION : multigenerations
  • 【毒性作用】 Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured before birth)
  • 【参考】 AEHLAU Archives of Environmental Health. (Heldref Pub., 4000 Albemarle St., NW, Washington, DC 20016) V.1- 1960- Volume(issue)/page/year: 23,102,1971
  • 【测试类型】 TDLo - Lowest published toxic dose
  • 【接触途径】 Oral
  • 【测试物种】 Rodent - mouseDOSE : 3636 mg/kgSEX/DURATION : female 1-18 day(s) after conception
  • 【毒性作用】 Reproductive - Fertility - abortion
  • 【参考】 52GUAX "Anorganische Stoffe in der Toxikologie and Kriminalistik, Symposium, Mosbach, Fed. Rep. Ger., 1983," Heppenheim, Fed. Rep. Ger., Verlag Dr. Dieter Helm, 1983 Volume(issue)/page/year: -,91,1983
  • 【测试类型】 TDLo - Lowest published toxic dose
  • 【接触途径】 Oral
  • 【测试物种】 Rodent - mouseDOSE : 8250 ug/kgSEX/DURATION : female 7-17 day(s) after conception
  • 【毒性作用】 Reproductive - Specific Developmental Abnormalities - immune and reticuloendothelial system Reproductive - Effects on Newborn - behavioral
  • 【参考】 CHYCDW Zhonghua Yufangyixue Zazhi. Chinese Journal of Preventive Medicine. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) Beginning history not known. Volume(issue)/page/year: 28,20,1994
  • 【测试类型】 TDLo - Lowest published toxic dose
  • 【接触途径】 Oral
  • 【测试物种】 Rodent - mouseDOSE : 1650 ug/kgSEX/DURATION : female 7-17 day(s) after conception
  • 【毒性作用】 Reproductive - Specific Developmental Abnormalities - Central Nervous System
  • 【参考】 CHYCDW Zhonghua Yufangyixue Zazhi. Chinese Journal of Preventive Medicine. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) Beginning history not known. Volume(issue)/page/year: 28,20,1994
  • 【测试类型】 TCLo - Lowest published toxic concentration
  • 【接触途径】 Inhalation
  • 【测试物种】 Rodent - mouseDOSE : 28500 ug/m3/4HSEX/DURATION : female 9-12 day(s) after conception
  • 【毒性作用】 Reproductive - Effects on Embryo or Fetus - cytological changes (including somatic cell genetic material) Reproductive - Specific Developmental Abnormalities - musculoskeletal system
  • 【参考】 JJATDK JAT, Journal of Applied Toxicology. (John Wiley & Sons Ltd., Baffins Lane, Chichester, W. Sussex PO19 1UD, UK) V.1- 1981- Volume(issue)/page/year: 5,61,1985
  • 【测试类型】 TCLo - Lowest published toxic concentration
  • 【接触途径】 Inhalation
  • 【测试物种】 Rodent - mouseDOSE : 260 ug/m3/4HSEX/DURATION : female 9-12 day(s) after conception
  • 【毒性作用】 Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
  • 【参考】 JJATDK JAT, Journal of Applied Toxicology. (John Wiley & Sons Ltd., Baffins Lane, Chichester, W. Sussex PO19 1UD, UK) V.1- 1981- Volume(issue)/page/year: 5,61,1985
    〖致突变数据〗
  • 【测试类型】 DNA repairTEST SYSTEM : Bacteria - Bacillus subtilis
  • 【剂量/时间】 50 mmol/L
  • 【参考】 MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 77,109,1980
  • 【测试类型】 Unscheduled DNA synthesisTEST SYSTEM : Human Lung
  • 【剂量/时间】 1 umol/L
  • 【参考】 MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 315,11,1994
  • 【测试类型】 DNA inhibitionTEST SYSTEM : Human HeLa cell
  • 【剂量/时间】 500 umol/L
  • 【参考】 MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 92,427,1982
  • 【测试类型】 Cytogenetic analysisTEST SYSTEM : Human Leukocyte
  • 【剂量/时间】 1200 nmol/L
  • 【参考】 MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 88,73,1981
  • 【测试类型】 Sister chromatid exchangeTEST SYSTEM : Human Lymphocyte
  • 【剂量/时间】 2 ug/cm3
  • 【参考】 BCTKAG Bromatologia i Chemia Toksykologiczna. (Ars Polona, POB 1001, 00-068 Warsaw 1, Poland) V.4- 1971- Volume(issue)/page/year: 19,255,1986
  • 【测试类型】 Micronucleus test
  • 【接触途径】 IntraperitonealTEST SYSTEM : Rodent - mouse
  • 【剂量/时间】 1 mg/kg
  • 【参考】 GNKAA5 Genetika (Moscow). For English translation, see SOGEBZ. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) No.1- 1965- Volume(issue)/page/year: 20,365,1984
  • 【测试类型】 DNA inhibition
  • 【接触途径】 OralTEST SYSTEM : Rodent - mouse
  • 【剂量/时间】 20 mL/kg
  • 【参考】 ARGEAR Archiv fuer Geschwulstforschung. (VEB Verlag Volk und Gesundheit Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1949- Volume(issue)/page/year: 51,605,1981
  • 【测试类型】 Cytogenetic analysis
  • 【接触途径】 OralTEST SYSTEM : Rodent - mouse
  • 【剂量/时间】 3696 mg/kg
  • 【参考】 CYTOAN Cytologia. (Japan Pub. Trading Co. (USA), 1255 Howard St., San Francisco, CA 94103) V.1- 1929- Volume(issue)/page/year: 52,445,1987
  • 【测试类型】 Cytogenetic analysisTEST SYSTEM : Rodent - mouse Cells - not otherwise specified
  • 【剂量/时间】 28500 ug/m3
  • 【参考】 JJATDK JAT, Journal of Applied Toxicology. (John Wiley & Sons Ltd., Baffins Lane, Chichester, W. Sussex PO19 1UD, UK) V.1- 1981- Volume(issue)/page/year: 5,61,1985
  • ◇◇◇综述◇◇◇
  • IARC Cancer Review:Human Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 2,48,1973 IARC Cancer Review:Human Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 23,39,1980 IARC Cancer Review:Animal Limited Evidence IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,100,1987 IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 2,48,1973 IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 23,39,1980 IARC Cancer Review:Group 1 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,100,1987 TOXICOLOGY REVIEW AMIHAB AMA Archives of Industrial Health. (Chicago, IL) V.11-21, 1955-60. For publisher information, see AEHLAU. Volume(issue)/page/year: 21,132,1960 TOXICOLOGY REVIEW ADTEAS Advances in Teratology. (New York, NY) V.1-5, 1966-72. Discontinued. Volume(issue)/page/year: 5,51,1972 TOXICOLOGY REVIEW PTPAD4 Pharmacology and Therapeutics, Part A: Chemotherapy, Toxicology and Metabolic Inhibitors. (Oxford, UK) V.1-2, 1976-78. For publisher information, see PHTHDT. Volume(issue)/page/year: 1,189,1976 TOXICOLOGY REVIEW 85DHAX "Medical and Biologic Effects of Environmental Pollutants Series," Washington, DC, National Academy of Sciences, 1972-77 Volume(issue)/page/year: As,-,1977
  • ◇◇◇美国标准和规章◇◇◇
  • EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 OSHA-cancer hazard CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1018,1987
  • ◇◇◇职业接触限量◇◇◇
  • OEL-AUSTRALIA;Carcinogen JAN 1993 OEL-BELGIUM;Carcinogen JAN 1993 OEL-FINLAND;Carcinogen JAN 1993 OEL-FRANCE:STEL 0.2 ppm;Carcinogen JAN 1993 OEL-GERMANY;Carcinogen JAN 1993 OEL-JAPAN:STEL 0.5 ppm;Carcinogen JAN 1993 OEL-THE PHILIPPINES:TWA 0.1 mg/m3;Carcinogen JAN 1993 OEL-SWITZERLAND:TWA 0.15 mg/m3 JAN 1993 OEL-UNITED KINGDOM:TWA 0.1 mg/m3 JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV
  • ◇◇◇NIOSH 标准发展和监测数据◇◇◇
    NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO ARSENIC, INORGANIC-air:CA CL 0.002 mg(As)/m3/15M
  • 【参考】 NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992
  • 【NIOSH 职业性接触鉴定数据】 NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 07570 No. of Facilities: 1284 (estimated) No. of Industries: 6 No. of Occupations: 6 No. of Employees: 3980 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 07570 No. of Facilities: 107 (estimated) No. of Industries: 8 No. of Occupations: 16 No. of Employees: 4657 (estimated) No. of Female Employees: 2001 (estimated)
  • ◇◇◇在美国的情况◇◇◇
  • EPA GENETOX PROGRAM 1988, Positive: B subtilis rec assay EPA TSCA Section 8(b) CHEMICAL INVENTORY EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998 NIOSH CURRENT INTELLIGENCE BULLETIN 14, 1976 NIOSH Analytical Method, 1994: Arsenic trioxide as As, 7901 NTP 7th Annual Report on Carcinogens, 1992 : known to be carcinogenic NTP Carcinogenesis studies; selected, October 1997
  • ◇◇◇全部数据完毕◇◇◇
 
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