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120-78-5

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摘 要:120-78-5, RTECS NUMBER : DL4550000 CHEMICAL NAME : Benzothiazole, 2,2'-dithiobis- CAS REGISTRY NUMBE
    ◇◇◇化学鉴别信息◇◇◇
  • 【RTECS 编号】 DL4550000
  • 【化学名】 Benzothiazole, 2,2'-dithiobis-
  • 【CAS 登记号】 120-78-5
  • 【BEILSTEIN 参考号】 0285796
  • 【参考】 4-27-00-01862 (Beilstein Handbook Reference)
  • 【上次更新时间】 199804
  • 【引用数据项】 18
  • 【分子式】 C14-H8-N2-S4
  • 【分子量】 332.48
  • 【维斯韦塞(氏)线的符号】 T56 BN DSJ CSS- CT56 BN DSJ
  • 【化合物描述】 Tumorigen Mutagen Reproductive Effector
  • 【别名】 * Altax * Benzothiazole disulfide * Benzothiazolyl disulfide * 2-Benzothiazolyl disulfide * Benzothiazyl disulfide * Bis(benzothiazolyl) disulfide * Bis(2-benzothiazyl) disulfide * Di-2-benzothiazolyl disulfide * Dibenzothiazolyl disulphide * Dibenzothiazyl disulfide * 2,2'-Dibenzothiazyl disulfide * Dibenzoylthiazyl disulfide * Dibenzthiazyl disulfide * 2,2'-Dithiobis(benzothiazole) * Dwusiarczek dwubenzotiazylu * MBTS * MBTS rubber accelerator * 2-Mercaptobenzothiazole disulfide * 2-Mercaptobenzothiazyl disulfide * Royal MBTS * Thiofide * USAF CY-5 * USAF EK-5432 * Vulkacit DM * Vulkacit DM/mgc
  • ◇◇◇卫生公害数据◇◇◇
    〖急性毒性数据〗
  • 【测试类型】 LD50 - Lethal dose, 50 percent kill
  • 【接触途径】 Oral
  • 【测试物种】 Rodent - rat
  • 【剂量/时间】 >12 gm/kg
  • 【毒性作用】 Details of toxic effects not reported other than lethal dose value
  • 【参考】 NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD755-358
  • 【测试类型】 LD50 - Lethal dose, 50 percent kill
  • 【接触途径】 Intraperitoneal
  • 【测试物种】 Rodent - rat
  • 【剂量/时间】 2600 mg/kg
  • 【毒性作用】 Details of toxic effects not reported other than lethal dose value
  • 【参考】 IPSTB3 International Polymer Science and Technology. (Rapra Technology Ltd., Shawbury, Shrewsbury, Shropshire SY4 4NR, UK) Volume(issue)/page/year: 3,93,1976
  • 【测试类型】 LD50 - Lethal dose, 50 percent kill
  • 【接触途径】 Oral
  • 【测试物种】 Rodent - mouse
  • 【剂量/时间】 7 gm/kg
  • 【毒性作用】 Details of toxic effects not reported other than lethal dose value
  • 【参考】 IPSTB3 International Polymer Science and Technology. (Rapra Technology Ltd., Shawbury, Shrewsbury, Shropshire SY4 4NR, UK) Volume(issue)/page/year: 3,93,1976
  • 【测试类型】 LD50 - Lethal dose, 50 percent kill
  • 【接触途径】 Intraperitoneal
  • 【测试物种】 Rodent - mouse
  • 【剂量/时间】 100 mg/kg
  • 【毒性作用】 Details of toxic effects not reported other than lethal dose value
  • 【参考】 NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD277-689
  • 【测试类型】 LD50 - Lethal dose, 50 percent kill
  • 【接触途径】 Intravenous
  • 【测试物种】 Rodent - mouse
  • 【剂量/时间】 180 mg/kg
  • 【毒性作用】 Details of toxic effects not reported other than lethal dose value
  • 【参考】 CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#02251
  • 【测试类型】 LD50 - Lethal dose, 50 percent kill
  • 【接触途径】 Administration onto the skin
  • 【测试物种】 Rodent - rabbit
  • 【剂量/时间】 >7940 mg/kg
  • 【毒性作用】 Details of toxic effects not reported other than lethal dose value
  • 【参考】 EPASR* United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. (U.S. Environmental Protection Agency, 401 M St., SW, Washington, DC 20460) History unknown. Volume(issue)/page/year: 8EHQ-1190-0987S
  • 〖其他多剂量毒性数据〗
  • 【测试类型】 TDLo - Lowest published toxic dose
  • 【接触途径】 Oral
  • 【测试物种】 Rodent - rat
  • 【剂量/时间】 9100 mg/kg/13W-I
  • 【毒性作用】 Liver - other changes Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - dehydrogenases
  • 【参考】 KHZDAN Khigiena i Zdraveopazvane. Hygiene and Sanitation. (Hemus, Blvd. Russki 6, Sofia, Bulgaria) V.9- 1966- Volume(issue)/page/year: 23,414,1980
  • 〖致肿瘤数据数据〗
  • 【测试类型】 TDLo - Lowest published toxic dose
  • 【接触途径】 Oral
  • 【测试物种】 Rodent - mouse
  • 【剂量/时间】 172 gm/kg/78W-I
  • 【毒性作用】 Tumorigenic - equivocal tumorigenic agent by RTECS criteria Lungs, Thorax, or Respiration - tumors Blood - tumors
  • 【参考】 NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: PB223-159
  • 〖繁殖数据〗
  • 【测试类型】 TDLo - Lowest published toxic dose
  • 【接触途径】 Parenteral
  • 【测试物种】 Rodent - ratDOSE : 400 mg/kgSEX/DURATION : female 4-11 day(s) after conception
  • 【毒性作用】 Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured before birth) Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
  • 【参考】 BEXBAN Bulletin of Experimental Biology and Medicine (English Translation). Translation of BEBMAE. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) V.41- 1956- Volume(issue)/page/year: 93,107,1982
  • 【测试类型】 TDLo - Lowest published toxic dose
  • 【接触途径】 Parenteral
  • 【测试物种】 Rodent - ratDOSE : 400 mg/kgSEX/DURATION : female 4-11 day(s) after conception
  • 【毒性作用】 Reproductive - Effects on Embryo or Fetus - fetal death
  • 【参考】 BEXBAN Bulletin of Experimental Biology and Medicine (English Translation). Translation of BEBMAE. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) V.41- 1956- Volume(issue)/page/year: 93,107,1982
  • 【测试类型】 TDLo - Lowest published toxic dose
  • 【接触途径】 Parenteral
  • 【测试物种】 Rodent - ratDOSE : 800 mg/kgSEX/DURATION : male 2 day(s) pre-mating female 2 day(s) pre-mating
  • 【毒性作用】 Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured before birth) Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
  • 【参考】 BEXBAN Bulletin of Experimental Biology and Medicine (English Translation). Translation of BEBMAE. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) V.41- 1956- Volume(issue)/page/year: 93,107,1982
  • 【测试类型】 TDLo - Lowest published toxic dose
  • 【接触途径】 Parenteral
  • 【测试物种】 Rodent - ratDOSE : 800 mg/kgSEX/DURATION : male 2 day(s) pre-mating female 2 day(s) pre-mating
  • 【毒性作用】 Reproductive - Effects on Embryo or Fetus - fetal death
  • 【参考】 BEXBAN Bulletin of Experimental Biology and Medicine (English Translation). Translation of BEBMAE. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) V.41- 1956- Volume(issue)/page/year: 93,107,1982
    〖致突变数据〗
  • 【测试类型】 Mutation in microorganismsTEST SYSTEM : Bacteria - Salmonella typhimurium
  • 【剂量/时间】 3333 ug/plate
  • 【参考】 EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 11(Suppl 12),1,1988
  • 【测试类型】 Mutation in microorganismsTEST SYSTEM : Rodent - mouse Lymphocyte
  • 【剂量/时间】 15 mg/L
  • 【参考】 ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 5,193,1983
  • ◇◇◇NIOSH 标准发展和监测数据◇◇◇
  • 【NIOSH 职业性接触鉴定数据】 NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84830 No. of Facilities: 897 (estimated) No. of Industries: 12 No. of Occupations: 28 No. of Employees: 11180 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 84830 No. of Facilities: 1533 (estimated) No. of Industries: 19 No. of Occupations: 42 No. of Employees: 50590 (estimated) No. of Female Employees: 11091 (estimated)
  • ◇◇◇在美国的情况◇◇◇
  • EPA TSCA Section 8(b) CHEMICAL INVENTORY EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998
  • ◇◇◇全部数据完毕◇◇◇
 
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